Originally Cherokee Indian territory, Johns Creek grew as settlers, enticed to the area by the promise of gold, built a number of trading posts during the 1830s. As settlers arrived in the area, the Cherokee moved out, forced from their homes by the then young federal government.
When Milton County dissolved in the 1930s, Fulton County absorbed Johns Creek. Some 50 years later, Georgia Tech graduates purchased land in the area to develop a planned community. They named it Technology Park/Johns Creek, and soon, more than 200 companies moved to the area.
During the 1980s and 1990s, Johns Creek witnessed profound population growth, and so in 2006, the city at long last incorporated.