Talmo, or "The Jewel of Jackson County" as its residents refer to it, is a small agricultural city with a rich history. Its name derives from the Creek Indian word "talomeco", which means “Home of the Chief Tallassee.” Settlers arrived in approximately 1840, but Talmo really began to grow in the 1900s when the Gainesville Midland constructed a side track through the city.
During this period and until 1919, Talmo was famous for its high quality staple cotton, recognized in the trade as "Talmo Cotton" or "Gold Cotton." In the 1920s the economic focus of the city turned away from cotton and toward livestock production. Georgia's “father of the commercial broiler production," M. E. “Ellis” Murphy began at that time producing broilers in the area. Today, Talmo, a popular living destination for Atlanta commuters, is still largely agricultural.